A Glasgow band that soundtracked a generation’s Saturday mornings is coming back to the States for the first time in over two decades.

BIS, the indie-pop trio behind The Powerpuff Girls’ original end theme, will perform at The Heroes of Townsville on November 7 at Glendale’s Alex Theatre. It’s their first U.S. concert in more than 25 years, and it’s happening alongside a full reunion of the show’s original voice cast and creative team.

The event brings together Catherine Cavadini (Blossom), Tara Strong (Bubbles), E.G. Daily (Buttercup), series creator Craig McCracken, and Lauren Faust. Linda Simensky moderates, with Eric Bauza hosting.

BIS made their name in the ’90s with tracks like “Kandy Pop” and “Eurodisco,” mixing pop hooks with punk energy and disco rhythms. But for a whole generation of animation fans, they’re the sound of Cartoon Network childhood. Their music also turned up in the Jet Set Radio games, cementing their cult status.

Saturday Morning Cartoons United is producing the fundraiser, with proceeds benefiting Starlight Children’s Foundation and the nonprofit’s ongoing animation celebration work. The night also features Next Friday: Magical Meow Meow, an indie animated short by Jen Nguyen and Mary Ramos, plus a pop-up marketplace and photo ops.

It’s a rare crossover moment: the voices, the creator, and the music that helped make The Powerpuff Girls a pop-culture fixture, all in one room.